名称:重组人AMIGO2/Adhesion molecule with Ig-like domain 2 ProteinProtein(C-6His);
产品说明(Description) Recombinant Human Amphoterin-induced Gene and ORF 2 is produced by our Mammalian expression system and the target gene encoding Val40-His393 is expressed with a 6His tag at the C-terminus. Accession #: Q86SJ2 Known as: Amphoterin-Induced Protein 2; AMIGO-2; Alivin-1; Differentially Expressed in Gastric Adenocarcinomas; DEGA; AMIGO2; ALI1 制剂(Formulation) Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. 质量控制(Quality Control) Purity: Greater than 90% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶(Reconstitution) Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存(Storage) Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. 背景(Background) Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY