产品资料

重组人Angiopoietin-like Protein 3/ANGPTL3 (17-220aa) Protein(C-6His)

如果您对该产品感兴趣的话,可以
产品名称: 重组人Angiopoietin-like Protein 3/ANGPTL3 (17-220aa) Protein(C-6His)
产品型号: PN100066-10ug
产品展商: PERFEMIKER
产品价格: 720.00 元
会员价格: 0.00 元
产品文档: 无相关文档
我要买:
产品已经成功添加到购物车
你添加了1件产品 查看购物车

简单介绍

重组人Angiopoietin-like Protein 3/ANGPTL3 (17-220aa) Protein(C-6His) 货号:PN100066 规格:10ug; 标签:C-6His; 来源:Human; 表达宿主:Human Cells


重组人Angiopoietin-like Protein 3/ANGPTL3 (17-220aa) Protein(C-6His)  的详细介绍

名称:重组人Angiopoietin-like Protein 3/ANGPTL3 (17-220aa) Protein(C-6His);



产品说明(Description)
Recombinant Human Angiopoietin-related Protein 3 is produced by our Mammalian expression system and the target gene encoding Ser17-Pro220 is expressed with a 6His tag at the C-terminus. 
Accession #: Q9Y5C1
Known as: Angiopoietin-related protein 3; ANGPTL3; Angiopoietin-5; ANG-5; Angiopoietin-like protein 3; ANGPT5

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through *****hood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. ANGPTL3 promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 expression in vivo is up-regulated by LXR agonists and down-regulated by insulin, leptin, and agonists of TRβ or PPARβ.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY