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重组小鼠Angiopoietin-related protein 4/ANGPTL4Protein(C-Fc)

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产品名称: 重组小鼠Angiopoietin-related protein 4/ANGPTL4Protein(C-Fc)
产品型号: PN100068-10ug
产品展商: PERFEMIKER
产品价格: 760.00 元
会员价格: 0.00 元
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简单介绍

重组小鼠Angiopoietin-related protein 4/ANGPTL4Protein(C-Fc) 货号:PN100068 规格:10ug; 标签:C-Fc; 来源:Mouse; 表达宿主:Human cells


重组小鼠Angiopoietin-related protein 4/ANGPTL4Protein(C-Fc)  的详细介绍

名称:重组小鼠Angiopoietin-related protein 4/ANGPTL4Protein(C-Fc);


产品说明(Description)
Recombinant Mouse Angiopoietin Like protein 4 is produced by our Mammalian expression system and the target gene encoding Lys167-Ser410 is expressed with a Fc tag at the C-terminus. 
Accession #: Q9Z1P8
Known as: Angiopoietin-related protein 4;425O18-1;Angiopoietin-like protein 4;Fasting-induced adipose factor;Hepatic fibrinogen/angiopoietin-related protein;HFARP;Secreted protein Bk89;Angptl4;Farp; Fiaf; Ng27

制剂(Formulation)
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)

保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.   

背景(Background)
Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY