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重组人Angiopoietin-related Protein 7/ANGPTL7 Protein(C-10His)

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产品名称: 重组人Angiopoietin-related Protein 7/ANGPTL7 Protein(C-10His)
产品型号: PN100069-10ug
产品展商: PERFEMIKER
产品价格: 840.00 元
会员价格: 0.00 元
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简单介绍

重组人Angiopoietin-related Protein 7/ANGPTL7 Protein(C-10His) 货号:PN100069 规格:10ug; 标签:C-10His; 来源:Human; 表达宿主:Human Cells


重组人Angiopoietin-related Protein 7/ANGPTL7 Protein(C-10His)  的详细介绍

名称:重组人Angiopoietin-related Protein 7/ANGPTL7 Protein(C-10His);



产品说明(Description)
Recombinant Human Angiopoietin-related Protein 7 is produced by our Mammalian expression system and the target gene encoding Gln27-Pro346 is expressed with a 10His tag at the C-terminus. 
Accession #: O43827
Known as: Angiopoietin-related protein 7; Angiopoietin-like factor; Angiopoietin-like protein 7; Cornea-derived transcript 6 protein; ANGPTL7; CDT6

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL7 shares 89% aa sequence identity with mouse and rat ANGPTL7. It is secreted as a 45-50kDa monomer that forms disulfide-linked homotrimers and tetramers via the coiled coil domain. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Its production is up-regulated in trabecular meshwork cells by glucocorticoids and TGF-β and in cartilage by TNF-α. Overexpression of ANGPTL7 in trabecular meshwork cells inhibits the production of collagen and proteoglycans. When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY