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重组人Anthrax toxin receptor 1/ANTXR1/ATRProtein(C-6His)

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产品名称: 重组人Anthrax toxin receptor 1/ANTXR1/ATRProtein(C-6His)
产品型号: PN100081-10ug
产品展商: PERFEMIKER
产品价格: 840.00 元
会员价格: 0.00 元
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简单介绍

重组人Anthrax toxin receptor 1/ANTXR1/ATRProtein(C-6His) 货号:PN100081 规格:10ug; 标签:C-6His; 来源:Human; 表达宿主:Human cells


重组人Anthrax toxin receptor 1/ANTXR1/ATRProtein(C-6His)  的详细介绍

名称:重组人Anthrax toxin receptor 1/ANTXR1/ATRProtein(C-6His);



产品说明(Description)
Recombinant Human Anthrax Toxin Receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu33-Lys321 is expressed with a 6His tag at the C-terminus. 
Accession #: Q9H6X2
Known as: Anthrax Toxin Receptor 1; Tumor Endothelial Marker 8; ANTXR1; ATR; TEM8

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY