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重组人ATG10/Ubiquitin-like-conjugating enzyme ATG10Protein(C-6His, N-T7 tag)

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产品名称: 重组人ATG10/Ubiquitin-like-conjugating enzyme ATG10Protein(C-6His, N-T7 tag)
产品型号: PN100114-10ug
产品展商: PERFEMIKER
产品价格: 1200.00 元
会员价格: 0.00 元
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简单介绍

重组人ATG10/Ubiquitin-like-conjugating enzyme ATG10Protein(C-6His, N-T7 tag) 货号:PN100114 规格:10ug; 标签:C-6His, N-T7 tag; 来源:Human; 表达宿主:E.coli


重组人ATG10/Ubiquitin-like-conjugating enzyme ATG10Protein(C-6His, N-T7 tag)  的详细介绍

名称:重组人ATG10/Ubiquitin-like-conjugating enzyme ATG10Protein(C-6His, N-T7 tag);


产品说明(Description)
Recombinant Human Autophagy Related 10 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Thr190 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. 
Accession #: Q9H0Y0
Known as: Ubiquitin-Like-Conjugating Enzyme ATG10; Autophagy-Related Protein 10; APG10-Like; ATG10

制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 8.0.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)

保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.   

背景(Background)
Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY