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重组人ATG3/Apg3L/Apg3p Protein(C-6His, N-T7 tag)

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产品名称: 重组人ATG3/Apg3L/Apg3p Protein(C-6His, N-T7 tag)
产品型号: PN100115-50ug
产品展商: PERFEMIKER
产品价格: 640.00 元
会员价格: 0.00 元
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简单介绍

重组人ATG3/Apg3L/Apg3p Protein(C-6His, N-T7 tag) 货号:PN100115 规格:50ug; 标签:C-6His, N-T7 tag; 来源:Human; 表达宿主:E.coli


重组人ATG3/Apg3L/Apg3p Protein(C-6His, N-T7 tag)  的详细介绍

名称:重组人ATG3/Apg3L/Apg3p Protein(C-6His, N-T7 tag);


产品说明(Description)
Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed. 
Accession #: Q9NT62
Known as: Ubiquitin-like-conjugating enzyme ATG3; Autophagy-related protein 3; APG3-like; hApg3; Protein PC3-96; ATG3; APG3; APG3L

制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH 8.0.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)

保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.   

背景(Background)
Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY