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重组人ATG4C/Autophagin-3Protein(C-6His)

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产品名称: 重组人ATG4C/Autophagin-3Protein(C-6His)
产品型号: PN100117-10ug
产品展商: PERFEMIKER
产品价格: 1200.00 元
会员价格: 0.00 元
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简单介绍

重组人ATG4C/Autophagin-3Protein(C-6His) 货号:PN100117 规格:10ug; 标签:C-6His; 来源:Human; 表达宿主:E.coli


重组人ATG4C/Autophagin-3Protein(C-6His)  的详细介绍

名称:重组人ATG4C/Autophagin-3Protein(C-6His);


产品说明(Description)
Recombinant Human Autophagy Related 4 Homolog C is produced by our E.coli expression system and the target gene encoding Met1-Leu458 is expressed with a 6His tag at the C-terminus. 
Accession #: Q96DT6
Known as: Cysteine Protease ATG4C; AUT-Like 3 Cysteine Endopeptidase; Autophagin-3; Autophagy-Related Cysteine Endopeptidase 3; Autophagy-Related Protein 4 homolog C; ATG4C; APG4C; AUTL1; AUTL3

制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0.

质量控制(Quality Control) 
Purity: Greater than 90% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)

保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.   

背景(Background)
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY