名称：重组人ATG5/Autophagy protein 5/APG5L/ASPProtein（None）；
产品说明(Description) Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed. Accession #: Q9H1Y0 Known as: Autophagy protein 5; APG5-like; Apoptosis-specific protein; APG5L; ASP; ATG5; 制剂（Formulation） Supplied as a 0.2 μm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 . 质量控制（Quality Control） Purity: Greater than 90% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶（Reconstitution） 保存（Storage） Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. 背景（Background） ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY