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重组小鼠Cathepsin B/CTSBProtein(C-6His)

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产品名称: 重组小鼠Cathepsin B/CTSBProtein(C-6His)
产品型号: PN100254-10ug
产品展商: PERFEMIKER
产品价格: 1200.00 元
会员价格: 0.00 元
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简单介绍

重组小鼠Cathepsin B/CTSBProtein(C-6His) 货号:PN100254 规格:10ug; 标签:C-6His; 来源:Mouse; 表达宿主:Human cells


重组小鼠Cathepsin B/CTSBProtein(C-6His)  的详细介绍

名称:重组小鼠Cathepsin B/CTSBProtein(C-6His);


产品说明(Description)
Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus. 
Accession #: P10605
Known as: Cathepsin B;Ctsb;Cathepsin B1

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY