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重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His)

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产品名称: 重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His)
产品型号: PN100041-10ug
产品展商: PERFEMIKER
产品价格: 1200.00 元
会员价格: 0.00 元
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简单介绍

重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His) 货号:PN100041 规格:10ug; 标签:N-6His; 来源:Human; 表达宿主:E.coli


重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His)  的详细介绍

名称:重组人Aldo-keto Reductase 1C4/AKR1C4Protein(N-6His);


产品说明(Description)
Recombinant Human Aldo-Keto Reductase Family 1 Member C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus. 
Accession #: P17516
Known as: Aldo-Keto Reductase Family 1 Member C4; 3-Alpha-HSD1; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Chlordecone Reductase; CDR; Dihydrodiol Dehydrogenase 4; DD-4; DD4; HAKRA; AKR1C4; CHDR

制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.

质量控制(Quality Control) 
Purity: Greater than 90% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)

保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.   

背景(Background)
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY