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重组人ARK1C3/Aldo-keto reductase family 1 member C3Protein(C-6His)

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产品名称: 重组人ARK1C3/Aldo-keto reductase family 1 member C3Protein(C-6His)
产品型号: PN100104-50ug
产品展商: PERFEMIKER
产品价格: 3520.00 元
会员价格: 0.00 元
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简单介绍

重组人ARK1C3/Aldo-keto reductase family 1 member C3Protein(C-6His) 货号:PN100104 规格:50ug; 标签:C-6His; 来源:Human; 表达宿主:Human cells


重组人ARK1C3/Aldo-keto reductase family 1 member C3Protein(C-6His)  的详细介绍

名称:重组人ARK1C3/Aldo-keto reductase family 1 member C3Protein(C-6His);


产品说明(Description)
Recombinant Human Aldo-Keto Reductase Family 1 Member C3 is produced by our Mammalian expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the C-terminus. 
Accession #: P42330
Known as: Aldo-Keto Reductase Family 1 Member C3; 17-Beta-Hydroxysteroid Dehydrogenase Type 5; 17-Beta-HSD 5; 3-Alpha-HSD Type II Brain; 3-Alpha-Hydroxysteroid Dehydrogenase Type 2; 3-Alpha-HSD Type 2; Chlordecone Reductase Homolog HAKRb; Dihydrodiol Dehydrogenase 3; DD-3; DD3; Dihydrodiol Dehydrogenase Type I; HA1753; Indanol Dehydrogenase; Prostaglandin F Synthase; Testosterone 17-Beta-Dehydrogenase 5; Trans-1;2-Dihydrobenzene-1;2-Diol Dehydrogenase; AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY