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重组人ARRB1/β-Arrestin 1Protein(C-6His)

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产品名称: 重组人ARRB1/β-Arrestin 1Protein(C-6His)
产品型号: PN100106-10ug
产品展商: PERFEMIKER
产品价格: 840.00 元
会员价格: 0.00 元
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简单介绍

重组人ARRB1/β-Arrestin 1Protein(C-6His) 货号:PN100106 规格:10ug; 标签:C-6His; 来源:Human; 表达宿主:E.coli


重组人ARRB1/β-Arrestin 1Protein(C-6His)  的详细介绍

名称:重组人ARRB1/β-Arrestin 1Protein(C-6His);


产品说明(Description)
Recombinant Human beta-Arrestin 1 is produced by our E.coli expression system and the target gene encoding Met1-Arg418 is expressed with a 6His tag at the C-terminus. 
Accession #: P49407
Known as: Beta-Arrestin-1; Arrestin Beta-1; ARRB1; ARR1

制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

质量控制(Quality Control) 
Purity: Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景(Background)
β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY