名称:重组人Asialoglycoprotein receptor 1/ASGPR1Protein(C-6His);
产品说明(Description) Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus. Accession #: P07306 Known as: Asialoglycoprotein Receptor 1; ASGP-R 1; ASGPR 1; C-Type Lectin Domain Family 4 Member H1; Hepatic Lectin H1; HL-1; ASGR1; CLEC4H1 制剂(Formulation) Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. 质量控制(Quality Control) Purity: Greater than 90% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶(Reconstitution) Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存(Storage) Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. 背景(Background) Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY