名称:重组人ATG4C/Autophagin-3Protein(C-6His);
产品说明(Description) Recombinant Human Autophagy Related 4 Homolog C is produced by our E.coli expression system and the target gene encoding Met1-Leu458 is expressed with a 6His tag at the C-terminus. Accession #: Q96DT6 Known as: Cysteine Protease ATG4C; AUT-Like 3 Cysteine Endopeptidase; Autophagin-3; Autophagy-Related Cysteine Endopeptidase 3; Autophagy-Related Protein 4 homolog C; ATG4C; APG4C; AUTL1; AUTL3 制剂(Formulation) Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. 质量控制(Quality Control) Purity: Greater than 90% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. 复溶(Reconstitution) 保存(Storage) Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. 背景(Background) Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide. 电泳(SDS-PAGE) FOR RESEARCH USE ONLY